60 New Mutations in Each of Us: Speed of Human Mutation Revealed in New Family Genetic Research
|12:54:55 AM, Wednesday, June 15, 2011|
"Each one of us receives approximately 60 new mutations in our genome from our parents. This striking value is reported in the first-ever direct measure of new mutations coming from mother and father in whole human genomes published today.
For the first time, researchers have been able to answer the questions: how many new mutations does a child have and did most of them come from mum or dad? The researchers measured directly the numbers of mutations in two families, using whole genome sequences from the 1000 Genomes Project. The results also reveal that human genomes, like all genomes, are changed by the forces of mutation: our DNA is altered by differences in its code from that of our parents. Mutations that occur in sperm or egg cells will be 'new' mutations not seen in our parents.
Although most of our variety comes from reshuffling of genes from our parents, new mutations are the ultimate source from which new variation is drawn. Finding new mutations is extremely technically challenging as, on average, only 1 in every 100 million letters of DNA is altered each generation.
Previous measures of the mutation rate in humans has either averaged across both sexes or measured over several generations. There has been no measure of the new mutations passed from a specific parent to a child among multiple individuals or families.
"We human geneticists have theorised that mutation rates might be different between the sexes or between people," explains Dr Matt Hurles, Senior Group Leader at the Wellcome Trust Sanger Institute, who co-led the study with scientists at Montreal and Boston, "We know now that, in some families, most mutations might arise from the mother, in others most will arise from the father. This is a surprise: many people expected that in all families most mutations would come from the father, due to the additional number of times that the genome needs to be copied to make a sperm, as opposed to an egg."
Professor Philip Awadalla,who also co-led the project and is at University of Montreal explained: "Today, we have been able to test previous theories through new developments in experimental technologies and our analytical algorithms. This has allowed us to find these new mutations, which are like very small needles in a very large haystack."
The unexpected findings came from a careful study of two families consisting of both parents and one child. The researchers looked for new mutations present in the DNA from the children that were absent from their parents' genomes. They looked at almost 6000 possible mutations in the genome sequences..."
North Korea Getting Very Close to Nuclear Missile, Says South Korea
|3:30:16 PM, Monday, June 13, 2011|
"According to South Korea's defense minister, North Korea may have created a nuclear warhead small enough to be launched in a missile. This is a first for those nutters, who had previously only detonated two nuclear devices that were too big for rockets.Today, a typical thermonuclear weapon weighs about 2,400 pounds (1,100 kg), and has a destructive capability of 1.2 megatons of TNT. Compare this to the 0.013 megatons of TNT of Little Boy, the 9,700-pound nuclear bomb dropped by Enola Gay over Hiroshima.
If South Korea is right, this type of warhead would allow North Korea to create missiles capable of reaching South Korea or Japan just few minutes after launch. These nuclear devices can use their current and tested rocket technology, completely destroying a city as large as Tokyo or Seoul.
North Korea is also working on a missile capable of reaching as far as the West Coast of the United States. According to NORAD (North American Aerospace Defense Command) and USNORTHCOM (US Northern Command), Kim Jong Il and his cronies failed on testing such a rocket in April 2009. However, the Guardian later reported that North Korea may actually be able to reach Hawaii. Whatever the outcome of those tests was, what is clear that they will not stop at that failure..."
-- Oh herro!!!
Ukranian Muslim Girl Stoned to Death After Participating in a Beauty Contest
|2:32:58 PM, Monday, June 13, 2011|
"A teenage Muslim girl was stoned to death under 'Sharia law' after taking part in a beauty contest in Ukraine.
Katya Koren, 19, was found dead in a village in the Crimea region near her home.
Friends said she liked wearing fashionable clothes and had come seventh in a beauty contest.Her battered body was buried in a forest and was found a week after she disappeared.
Police have opened a murder investigation and are looking into claims that three Muslim youths killed her, claiming her death was justified under Islam.
One of the three - named as 16-year-old Bihal Gaziev - is under arrest and told police that Katya had 'violated the laws of Sharia'. Gaziev has said he has no regrets about her death..."
Three Arrested, Accused of Illegally Feeding Homeless
|2:16:32 PM, Monday, June 13, 2011|
"Members of Orlando Food Not Bombs were arrested Wednesday when police said they violated a city ordinance by feeding the homeless in Lake Eola Park.
Jessica Cross, 24, Benjamin Markeson, 49, and Jonathan "Keith" McHenry, 54, were arrested at 6:10 p.m. on a charge of violating the ordinance restricting group feedings in public parks. McHenry is a co-founder of the international Food Not Bombs movement, which began in the early 1980s.
The group lost a court battle in April, clearing the way for the city to enforce the ordinance. It requires groups to obtain a permit and limits each group to two permits per year for each park within a 2-mile radius of City Hall.
Arrest papers state that Cross, Markeson and McHenry helped feed 40 people Wednesday night. The ordinance applies to feedings of more than 25 people..."
Sak Noel - Loca People
|11:50:50 PM, Sunday, June 12, 2011|
Sami Yusuf - You Came To Me
|6:00:09 PM, Sunday, June 12, 2011|
Crows Dive-Bombing Cops in Everett ‘Like Velociraptors’
|5:55:45 PM, Sunday, June 12, 2011|
"Who invited Alfred Hitchcock to the Everett Police Department’s north precinct?
Like a scene out of the famous director’s film “The Birds,” three angry crows have been dive-bombing police officers as they dash across the parking lot to their cars.
“They’re like velociraptors,” Lt. Bob Johns told the Everett Herald.
Crows are paticularly adept at recognizing faces, meaning you don’t want to get on their bad side. University of Washington researchers recently determined crows have an uncanny ability to remember faces — and they act out if they feel threatened.
Now Everett police officers are dealing with a literal game of Angry Birds..."
U.S. Underwrites Internet Detour Around Censors
|5:49:19 PM, Sunday, June 12, 2011|
"The Obama administration is leading a global effort to deploy “shadow” Internet and mobile phone systems that dissidents can use to undermine repressive governments that seek to silence them by censoring or shutting down telecommunications networks.
The effort includes secretive projects to create independent cellphone networks inside foreign countries, as well as one operation out of a spy novel in a fifth-floor shop on L Street in Washington, where a group of young entrepreneurs who look as if they could be in a garage band are fitting deceptively innocent-looking hardware into a prototype “Internet in a suitcase.”
Financed with a $2 million State Department grant, the suitcase could be secreted across a border and quickly set up to allow wireless communication over a wide area with a link to the global Internet.
The American effort, revealed in dozens of interviews, planning documents and classified diplomatic cables obtained by The New York Times, ranges in scale, cost and sophistication.
Some projects involve technology that the United States is developing; others pull together tools that have already been created by hackers in a so-called liberation-technology movement sweeping the globe..."
UK Spies Hack al-Qaida, Replace Bomb Info With Cupcake Recipes
|1:34:48 AM, Saturday, June 11, 2011|
"British spies hacked into an al-Qaida website to replace instructions on how to build a bomb with recipes for making cupcakes, newspapers reported on Friday.
The cyber offensive took place last year when the English language magazine called Inspire, aimed at Muslims in the West, was launched by supporters of al-Qaida in the Arabian Peninsula (AQAP).
British intelligence officers based at the Government Communications Headquarters (GCHQ), the state eavesdropping service, attacked the 67-page magazine, leaving most of it garbled, British newspapers said.
Instead of being able to read how to "Make a Bomb in the Kitchen of Your Mom," readers were greeted with computer code which actually contained recipes from The Best Cupcakes in America, published by U.S. chat show host Ellen DeGeneres.
The Washington Post reported that the British action followed a dispute between the CIA and the newly formed U.S. Cyber Command.
The cyber unit had wanted to block the al Qaeda magazine but the CIA, which had countered such an attack would expose sources and intelligence methods, won the debate and declined to allow an attack on Inspire..."
Ice Kayaking in Alaska
|12:11:26 AM, Saturday, June 11, 2011|
-- Time to get a true white water kayak and drive to Alaska!!!
Voyager Probes Discover Bubbles at Solar System’s Edge
|11:56:09 PM, Friday, June 10, 2011|
"The Voyager missions have yielded many surprising discoveries about our solar system and, despite being 9 billion miles away from Earth, the data continues to pour in. Now, scientists at NASA are saying that they have made sense of some surprising readings from the spacecraft over the past few years. Their data indicates that the edge of the solar system is a frothy stew of magnetic bubbles.
For years it was assumed that the heliosheath, the outer limit of our sun’s magnetic field and the boarder of galactic space, was composed of graceful arcs of magnetic energy that curved back toward the sun. The reality is far less neat and tidy. Instead of arcs, the magnetic field is broken into a membrane of distinct bubbles, each about 100 million miles wide. The whole mix is also apparently writhing around, its movement being compared to bubbles from a jacuzzi jet.
Don’t worry, if none of this makes any sense, there’s a soothing and explanatory video at the end of this post. With pictures!
While it was a surprising discovery, scientists believe they understand how this bubbly barrier came to be. Because the sun’s spin has wobble to it, its magnetic field is twisted into ripples. At the edge of the solar system, those ripples bunch together and eventually split into massive magnetic bubbles.
With a working hypothesis about the nature of the bubbles, the next question is how this discovery changes our understanding of the solar system’s interaction with the rest of the galaxy. For instance, our solar system is constantly bombarded with high-energy cosmic rays spewed out from other celestial bodies. The sun’s magnetic field helps to deflect most of these away from us, but how the rays interact with the bubbles is still unknown..."
Rat Infestation on Australian Farms
|9:49:36 PM, Friday, June 10, 2011|
Eminem - I'm On Everything
|12:24:56 AM, Friday, June 10, 2011|
The First Globular Cluster Outside of Our Galaxy
|12:24:36 AM, Friday, June 10, 2011|
""This nebula had such a resemblance to a comet in its form and brightness that I endeavored to find others, so that astronomers would not confuse these same nebulae with comets just beginning to shine." -Charles Messier
Astronomers have been scouring the skies for new discoveries since long before the invention of the telescope. Why, just with the naked eye and some dark skies, anyone can discover about 6,000 stars, five major planets, the Milky Way, and the occasional very faint nebula.
And of course, if you're very fortunate and very diligent, you could have been among the first to discover whenever a new comet brightened and suddenly appeared! By time comets get relatively close to the Sun, their tails become bright and extended, and often easily visible to the naked eye.
But the telescope changed everything. Because now, for the first time, you could discover a comet when it was still very faint. When it was, in fact, still invisible to the naked eye, but where a careful observer would notice an object where there previously was none. Something, perhaps, like 2004's Comet Machholz..."
NATO Chief Rasmussen Grilled LIVE on RT Over Libya Assault
|12:02:17 AM, Friday, June 10, 2011|
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